Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ CXCR2 antagonist, Cpd 19
The CXCR2 antagonist, Cpd 19, also referenced under CAS 473728-67-5, controls the biological activity of CXCR2.
MilliporeSigma™ Calbiochem™ Pirenzepine Dihydrochloride
An antagonist selective for mAChR subtype M1.
MilliporeSigma™ Calbiochem™ InSolution™ Phorbol-12-myristate-13-acetate
Most commonly-used phorbol ester
MilliporeSigma™ Calbiochem™ mTOR Activator, MHY1485
mTOR Activator, MHY1485, CAS Number: 326914-06-1, is a cell-permeable activator of mTOR that inhibits autophagy by suppressing the fusion between autophagosomes and lysosomes.
MilliporeSigma™ Calbiochem™ Dicoumarol
A cell-permeable quinone reductase inhibitor with anticoagulant properties.
MilliporeSigma™ Calbiochem™ PAF Receptor Antagonist, ABT-491
The PAF Receptor Antagonist, ABT-491, also referenced under CAS 189689-94-9, controls the biological activity of PAF Receptor. This small molecule/inhibitor is primarily used for Membrane applications.
MilliporeSigma™ Calbiochem™ Histone Deacetylase Inhibitor VI, HNHA
The Histone Deacetylase Inhibitor VI, HNHA, also referenced under CAS 926908-04-5, controls the biological activity of Histone Deacetylase.
MilliporeSigma™ Calbiochem™ Adenosine 3',5'-cyclic Monophosphate, N6,O2'-Dibutyryl-, Sodium Salt
This Dibutyryl-cAMP, CAS 16980-89-5, is a cell-permeable cAMP analog that preferentially activates PKA.
MilliporeSigma™ Calbiochem™ IGF-1R Inhibitor, PPP
The IGF-1R Inhibitor, PPP, also referenced under CAS 477-47-4, controls the biological activity of IGF-1R. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ TNF-TNFR Interaction Modulator, C87
Inhibits TNFα/β-stimulated biological activity by modulating, but not abolishing, TNF-TNFR interaction via direct TNF affinity interaction (KD = 110 nM).
MilliporeSigma™ Calbiochem™ PTP Inhibitor V, PHPS1
The PTP Inhibitor V, PHPS1, also referenced under CAS 314291-83-3, controls the biological activity of PTP. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ AEBSF, Hydrochloride
AEBSF, CAS 30827-99-7, is a specific irreversible inhibitor of chymotrypsin, kallikrein, plasmin, thrombin, trypsin, and related thrombolytic enzymes. A nontoxic alternative to PMSF and DFP.
MilliporeSigma™ Calbiochem™ D-Val-Phe-Lys Chloromethyl Ketone, Dihydrochloride
Selective irreversible inhibitor of plasmin with high selectivity for plasmin (IC50 = 100 pM for human plasmin) over urokinase.
MilliporeSigma™ Calbiochem™ Apamin, Bee Venom
Polypeptide neurotoxin known to pass through the blood-brain barrier.
MilliporeSigma™ Calbiochem™ Adenosine 3',5'-cyclic Monophosphorothioate, 8-Bromo-, Rp-Isomer, Sodium Salt
A potent, cell-permeable, and reversible metabolically-stable cAMP antagonist that inhibits cAMP-dependent protein kinase and shows preference for PKA type I.